Polyphenol-induced improvements in glucose metabolism are associated with bile acid signaling to intestinal farnesoid X receptor
Introduction Bile acid (BA) biotransformation by gut bacteria impacts BA profile and signaling to nuclear receptors, such as the farnesoid X receptor (FXR) regulating glucose metabolism. Altered BA-FXR signaling was therefore investigated as a potential mechanism linking polyphenol-induced gut bacte...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-04-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/8/1/e001386.full |