Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection

Comparison of immune responses to Loa loa stage-specific antigen extracts in Loa loa-exposed BALB/c mice upon clearance of infection

Abstract Background Different immune mechanisms are capable of killing developmental stages of filarial nematodes and these mechanisms are also likely to vary between the primary and a challenge infection. However, the lack of a detailed analysis of cytokine, chemokine and immunoglobulin levels in h...

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Main Authors: Valerine C. Chunda, Manuel Ritter, Ayukenchengamba Bate, Narcisse V. T. Gandjui, Mathias E. Esum, Fanny F. Fombad, Abdel J. Njouendou, Patrick W. C. Ndongmo, Mark J. Taylor, Achim Hoerauf, Laura E. Layland, Joseph D. Turner, Samuel Wanji
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Parasites & Vectors
Subjects:
Recall immune responses
Re-stimulation
Immunoglobulins
Chemokines
Cytokines
Microfilariae
Online Access:https://doi.org/10.1186/s13071-020-3921-x

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