On the Corner of Models and Cure: Gene Editing in Cystic Fibrosis

On the Corner of Models and Cure: Gene Editing in Cystic Fibrosis

Cystic fibrosis (CF) is a severe genetic disease for which curative treatment is still lacking. Next generation biotechnologies and more efficient cell-based and in vivo disease models are accelerating the development of novel therapies for CF. Gene editing tools, like CRISPR-based systems, can be u...

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Bibliographic Details
Main Authors: Marjolein Ensinck, Angélique Mottais, Claire Detry, Teresinha Leal, Marianne S. Carlon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
cystic fibrosis
CFTR
gene therapy
gene editing
CF cell models
CF animal models
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.662110/full

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