Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-κB pathways

Abstract Anticancer drug like Cisplatin are associated with serious problem like nephrotoxicity. The effect of Kaempferol is a plant-derived flavonoid compound. The present work evaluated the effect of Kaempferol in mouse model of Cisplatin mediated nephrotoxicity also the involved mechanism. Oxidat...

Full description

Bibliographic Details
Main Authors: Zhu Wang, Wansen Sun, Xi Sun, Ye Wang, Meilan Zhou
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:AMB Express
Online Access:http://link.springer.com/article/10.1186/s13568-020-00993-w