Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice.

BACKGROUND:In mammals the interplay between the peripheral nervous system (PNS) and adipose tissue is widely unexplored. We have employed mice, which develop an adult onset of obesity due to the lack the neuronal specific transcription factor Nscl-2 to investigate the interplay between the nervous s...

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Bibliographic Details
Main Authors: Karen Ruschke, Henning Ebelt, Nora Klöting, Thomas Boettger, Kay Raum, Matthias Blüher, Thomas Braun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2677458?pdf=render