Junctional Modulation of Round Window Membrane Enhances Dexamethasone Uptake into the Inner Ear and Recovery after NIHL

Junctional Modulation of Round Window Membrane Enhances Dexamethasone Uptake into the Inner Ear and Recovery after NIHL

Delivery of substances into the inner ear via local routes is increasingly being used in clinical treatment. Studies have focused on methods to increase permeability through the round window membrane (RWM) and enhance drug diffusion into the inner ear. However, the clinical applications of those met...

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Bibliographic Details
Main Authors: Seong-Hun Jeong, Yoonjoong Kim, Ah-Ra Lyu, Sun-Ae Shin, Tae Hwan Kim, Yang Hoon Huh, A Reum Je, Akanksha Gajibhiye, Yang Yu, Yongde Jin, Min Jung Park, Yong-Ho Park
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
cochlea
round window membrane
RWM
noise-induced hearing loss
NIHL
sodium caprate
Online Access:https://www.mdpi.com/1422-0067/22/18/10061

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