Genetic factors control nicotine self-administration in isogenic adolescent rat strains.

Adult cigarette smokers usually become dependent on cigarettes during adolescence. Despite recent advances in addiction genetics, little data delineates the genetic factors that account for the vulnerability of humans to smoke tobacco. We studied the operant nicotine self-administration (SA) behavio...

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Bibliographic Details
Main Authors: Hao Chen, Katie A Hiler, Elizabeth A Tolley, Shannon G Matta, Burt M Sharp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429443?pdf=render