Apigenin-7-Glycoside Prevents LPS-Induced Acute Lung Injury via Downregulation of Oxidative Enzyme Expression and Protein Activation through Inhibition of MAPK Phosphorylation

Apigenin-7-Glycoside Prevents LPS-Induced Acute Lung Injury via Downregulation of Oxidative Enzyme Expression and Protein Activation through Inhibition of MAPK Phosphorylation

Apigenin-7-glycoside (AP7Glu) with multiple biological activities is a flavonoid that is currently prescribed to treat inflammatory diseases such as upper respiratory infections. Recently, several studies have shown that its anti-inflammatory activities have been strongly linked to the inhibition of...

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Bibliographic Details
Main Authors: Kun-Cheng Li, Yu-Ling Ho, Wen-Tsong Hsieh, Shyh-Shyun Huang, Yuan-Shiun Chang, Guan-Jhong Huang
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
acute lung injury
apigenin-7-glycoside
lipopolysaccharide (LPS)
AOEs (antioxidative enzymes)
HO-1 (heme oxygenase-1)
MAPK
Online Access:http://www.mdpi.com/1422-0067/16/1/1736

Internet

http://www.mdpi.com/1422-0067/16/1/1736

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