Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome

Matrix metalloproteinase-9 deletion rescues auditory evoked potential habituation deficit in a mouse model of Fragile X Syndrome

Sensory processing deficits are common in autism spectrum disorders, but the underlying mechanisms are unclear. Fragile X Syndrome (FXS) is a leading genetic cause of intellectual disability and autism. Electrophysiological responses in humans with FXS show reduced habituation with sound repetition...

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Bibliographic Details
Main Authors: Jonathan W. Lovelace, Teresa H. Wen, Sarah Reinhard, Mike S. Hsu, Harpreet Sidhu, Iryna M. Ethell, Devin K. Binder, Khaleel A. Razak
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Neurobiology of Disease
Subjects:
Fragile X Syndrome
Autism
Auditory cortex
Sensory hypersensitivity
Cortical event related potentials
Matrix metalloproteinase-9
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300237

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http://www.sciencedirect.com/science/article/pii/S0969996116300237

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