Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma

Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma

Patients receiving immunosuppressive drugs to prevent organ transplant rejection exhibit a greatly increased risk of developing cutaneous squamous cell carcinoma (SCC). However, not all immunosuppressive drugs confer the same risk. Randomised, controlled trials demonstrate that switching renal trans...

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Bibliographic Details
Main Authors: Ji-Won Jung, Margaret Veitch, Jennifer A. Bridge, Nana H. Overgaard, Jazmina L. Cruz, Richard Linedale, Michael E. Franklin, Nicholas A. Saunders, Fiona Simpson, Ian H. Frazer, Raymond J. Steptoe, James W. Wells
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:OncoImmunology
Subjects:
t cells
memory
skin
transplantation
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1479627

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