Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function

Metformin during Pregnancy: Effects on Offspring Development and Metabolic Function

Maternal obesity during pregnancy and gestational diabetes mellitus (GDM) are both associated with of several postnatal diseases in the offspring, including obesity, early onset hypertension, diabetes mellitus, and reproductive alterations. Metformin is an oral drug that is being evaluated to treat...

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Bibliographic Details
Main Authors: Gonzalo Jorquera, Bárbara Echiburú, Nicolás Crisosto, Ramón Sotomayor-Zárate, Manuel Maliqueo, Gonzalo Cruz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
metformin
pregnancy
polycystic ovary syndrome
diabetes mellitus
postnatal
bodyweight
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00653/full

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