Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice

Revealing the Complexity in CD8 T Cell Responses to Infection in Inbred C57B/6 versus Outbred Swiss Mice

Recent work has suggested that current mouse models may underrepresent the complexity of human immune responses. While most mouse immunology studies utilize inbred mouse strains, it is unclear if conclusions drawn from inbred mice can be extended to all mouse strains or generalized to humans. We rec...

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Bibliographic Details
Main Authors:	Matthew D. Martin, Derek B. Danahy, Stacey M. Hartwig, John T. Harty, Vladimir P. Badovinac
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-11-01
Series:	Frontiers in Immunology
Subjects:	CD8 T cells immunologic memory outbred mice memory phenotypes protection against re-infection
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01527/full

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