Effect of Gliotoxin on Human Polymorphonuclear Neutrophils

Objectives:Candida albicans is known to produce gliotoxin, which has several prominent biological effects, including immunosuppression. interference with host defenses may arise from the effects of this toxin on leukocyte structure and function.

Bibliographic Details
Main Authors: D. T. Shah, S. Jackman, J. Engle, B. Larsen
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Infectious Diseases in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/S1064744998000349
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spelling doaj-a7ef91d3e29b4e008c07d986d5f8965c2020-11-24T23:17:47ZengHindawi LimitedInfectious Diseases in Obstetrics and Gynecology1064-74491098-09971998-01-016416817510.1155/S1064744998000349Effect of Gliotoxin on Human Polymorphonuclear NeutrophilsD. T. Shah0S. Jackman1J. Engle2B. Larsen3Department of Pathology, Marshall University School of Medicine, Huntington, WV, USADepartment of Microbiology, Immunology & Molecular Genetics, Marshall University School of Medicine, Huntington, WV, USADepartment of Microbiology, Immunology & Molecular Genetics, Marshall University School of Medicine, Huntington, WV, USAUniversity of Osteopathic Medicine and Health Sciences, Des Moines, IA, USAObjectives:Candida albicans is known to produce gliotoxin, which has several prominent biological effects, including immunosuppression. interference with host defenses may arise from the effects of this toxin on leukocyte structure and function.http://dx.doi.org/10.1155/S1064744998000349
collection DOAJ
language English
format Article
sources DOAJ
author D. T. Shah
S. Jackman
J. Engle
B. Larsen
spellingShingle D. T. Shah
S. Jackman
J. Engle
B. Larsen
Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
Infectious Diseases in Obstetrics and Gynecology
author_facet D. T. Shah
S. Jackman
J. Engle
B. Larsen
author_sort D. T. Shah
title Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
title_short Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
title_full Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
title_fullStr Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
title_full_unstemmed Effect of Gliotoxin on Human Polymorphonuclear Neutrophils
title_sort effect of gliotoxin on human polymorphonuclear neutrophils
publisher Hindawi Limited
series Infectious Diseases in Obstetrics and Gynecology
issn 1064-7449
1098-0997
publishDate 1998-01-01
description Objectives:Candida albicans is known to produce gliotoxin, which has several prominent biological effects, including immunosuppression. interference with host defenses may arise from the effects of this toxin on leukocyte structure and function.
url http://dx.doi.org/10.1155/S1064744998000349
work_keys_str_mv AT dtshah effectofgliotoxinonhumanpolymorphonuclearneutrophils
AT sjackman effectofgliotoxinonhumanpolymorphonuclearneutrophils
AT jengle effectofgliotoxinonhumanpolymorphonuclearneutrophils
AT blarsen effectofgliotoxinonhumanpolymorphonuclearneutrophils
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