Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma

Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma

<p>Abstract</p> <p>Background</p> <p>Neuroblastoma is a childhood cancer derived from immature cells of the sympathetic nervous system. The disease is clinically heterogeneous, ranging from neuronal differentiated benign ganglioneuromas to aggressive metastatic tumours...

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Bibliographic Details
Main Authors: Tømte Ellen, Buechner Jochen, Haug Bjørn, Henriksen Jørn R, Løkke Cecilie, Flaegstad Trond, Einvik Christer
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/11/1

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