Evaluation of nitazoxanide treatment following triclabendazole failure in an outbreak of human fascioliasis in Upper Egypt.

BACKGROUND:Fascioliasis is a neglected zoonosis with major public health implications in humans. Although triclabendazole (TCBZ) is the drug of choice, there are records of TCBZ failure worldwide. TCBZ-resistant fascioliasis is treated with alternative approved drugs including nitazoxanide (NTZ), wi...

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Main Authors: Haidi Karam-Allah Ramadan, Waleed Attia Hassan, Nahed Ahmed Elossily, Alzahraa Abdelraouf Ahmad, Adnan Ahmed Mohamed, Alaa Soliman Abd-Elkader, Eman M Nagiub Abdelsalam, Hani M J Khojah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007779