Influence of the <i>FCGR2A</i> rs1801274 and <i>FCGR3A</i> rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis

Influence of the <i>FCGR2A</i> rs1801274 and <i>FCGR3A</i> rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is an immunosuppressant indicated for treatment of rheumatoid arthritis (RA). Effectiveness might be influenced by clinical RA variants and single-nucleotide polymorphisms (SNPs) in genes encoding protein FCGR2A (His131Arg) and FCGR3A (Phe158Val) involved in pharmacokinetics of ABA....

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Bibliographic Details
Main Authors: Noelia Márquez Pete, María del Mar Maldonado Montoro, Cristina Pérez Ramírez, Fernando Martínez Martínez, Juan Enrique Martínez de la Plata, Abdelali Daddaoua, Alberto Jiménez Morales
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Journal of Personalized Medicine
Subjects:
rheumatoid arthritis
abatacept
<i>FCGR2A</i>
FCGR3A
effectiveness
polymorphisms
Online Access:https://www.mdpi.com/2075-4426/11/6/573

Internet

https://www.mdpi.com/2075-4426/11/6/573

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