Study of the cytoxin-associated gene a (CagA gene) in Helicobacter pylori using gastric biopsies of Iraqi patients
Background and Aims: The Helicobacter pylori CagA gene is a major virulence factor that plays an important role in gastric pathologies. The size variation of CagA gene, which is dependent on the 3′ repeat region, contains one or more Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs and CagA multimerization (CM) m...
Main Authors: | Elham A Kalaf, Zahra M Al-Khafaji, Nahi Y Yassen, Fadel A AL-Abbudi, Saad N Sadwen |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2013-01-01
|
Series: | The Saudi Journal of Gastroenterology |
Subjects: | |
Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2013;volume=19;issue=2;spage=69;epage=74;aulast=Kalaf |
Similar Items
-
Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins
by: Takeru Hayashi, et al.
Published: (2017-09-01) -
<i>Helicobacter pylori</i> CagA EPIYA Motif Variations Affect Metabolic Activity in B Cells
by: Sebastian Diechler, et al.
Published: (2021-08-01) -
Diversity of 3′ variable region of cagA gene in Helicobacter pylori strains isolated from Chinese population
by: Zhijing Xue, et al.
Published: (2021-04-01) -
Higher frequency of cagA EPIYA-C Phosphorylation Sites in <it>H. pylori</it> strains from first-degree relatives of gastric cancer patients
by: Queiroz Dulciene MM, et al.
Published: (2012-08-01) -
Role of <it>Helicobacter pylori </it><it>cagA</it> EPIYA motif and <it>vacA</it> genotypes for the development of gastrointestinal diseases in Southeast Asian countries: a meta-analysis
by: Sahara Shu, et al.
Published: (2012-09-01)