The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility

Kerstin J Frank,1,3 Ulrich Westedt,2 Karin M Rosenblatt,2 Peter Hölig,2 Jörg Rosenberg,2 Markus Mägerlein,2 Gert Fricker,3 Martin Brandl11Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Odense, Denmark; 2Abbott GmbH and Co. KG, Lu...

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Bibliographic Details
Main Authors: Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M
Format: Article
Language:English
Published: Dove Medical Press 2012-11-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/the-amorphous-solid-dispersion-of-the-poorly-soluble-abt-102-forms-nan-a11504