Essential oils from Syzygium aromaticum and Zingiber officinale, administered alone or in combination with benznidazole, reduce the parasite load in mice orally inoculated with Trypanosoma cruzi II

Essential oils from Syzygium aromaticum and Zingiber officinale, administered alone or in combination with benznidazole, reduce the parasite load in mice orally inoculated with Trypanosoma cruzi II

Abstract Background Trypanosoma cruzi is the etiological agent of Chagas disease (CD) or American trypanosomiasis, an important public health problem in Latin America. Benznidazole (BZ), a drug available for its treatment, has limited efficacy and significant side effects. Essential oils (EOs) have...

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Bibliographic Details
Main Authors: Marcella Paula Mansano Sarto, Hevillyn Fernanda Lucas da Silva, Nilma de Souza Fernandes, Ana Paula de Abreu, Gerson Zanusso Junior, Max Jean de Ornelas Toledo
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Trypanosoma cruzi
Mice
Syzygium aromaticum
Zingiber officinale
Drug combination
Oral Chagas disease
Online Access:https://doi.org/10.1186/s12906-021-03248-8

Internet

https://doi.org/10.1186/s12906-021-03248-8

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