Automated multiplex genome-scale engineering in yeast

Genome-scale engineering is a powerful technique for understanding biology and designing microorganisms but has been limited to bacterial species. Here the authors present an automated platform for genome-scale engineering inSaccharomyces cerevisiaeusing CRISPR-Cas and RNAi.

Bibliographic Details
Main Authors: Tong Si, Ran Chao, Yuhao Min, Yuying Wu, Wen Ren, Huimin Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15187