I-II loop structural determinants in the gating and surface expression of low voltage-activated calcium channels.

I-II loop structural determinants in the gating and surface expression of low voltage-activated calcium channels.

The intracellular loops that interlink the four transmembrane domains of Ca(2+)- and Na(+)-channels (Ca(v), Na(v)) have critical roles in numerous forms of channel regulation. In particular, the intracellular loop that joins repeats I and II (I-II loop) in high voltage-activated (HVA) Ca(2+) channel...

Full description

Bibliographic Details
Main Authors: Joel P Baumgart, Iuliia Vitko, Isabelle Bidaud, Artem Kondratskyi, Philippe Lory, Edward Perez-Reyes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18714336/pdf/?tool=EBI

Similar Items

Similar Items