Efficacy and safety of re-treatment with the same artemisinin-based combination treatment (ACT) compared with an alternative ACT and quinine plus clindamycin after failure of first-line recommended ACT (QUINACT): a bicentre, open-label, phase 3, randomised controlled trial

Efficacy and safety of re-treatment with the same artemisinin-based combination treatment (ACT) compared with an alternative ACT and quinine plus clindamycin after failure of first-line recommended ACT (QUINACT): a bicentre, open-label, phase 3, randomised controlled trial

Summary: Background: Quinine or alternative artemisinin-based combination treatment (ACT) is the recommended rescue treatment for uncomplicated malaria. However, patients are often re-treated with the same ACT though it is unclear whether this is the most suitable approach. We assessed the efficacy...

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Main Authors: Hypolite Muhindo Mavoko, DrPhD, Carolyn Nabasumba, MD, Raquel Inocêncio da Luz, PhD, Halidou Tinto, PhD, Umberto D'Alessandro, ProfPhD, Andrew Kambugu, MD, Vito Baraka, MSc, Anna Rosanas-Urgell, PhD, Pascal Lutumba, ProfPhD, Jean-Pierre Van geertruyden, PhD
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:The Lancet Global Health
Online Access:http://www.sciencedirect.com/science/article/pii/S2214109X16302364

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