MAVS O-GlcNAcylation Is Essential for Host Antiviral Immunity against Lethal RNA Viruses

MAVS O-GlcNAcylation Is Essential for Host Antiviral Immunity against Lethal RNA Viruses

Summary: It is known that lethal viruses profoundly manipulate host metabolism, but how the metabolism alternation affects the immediate host antiviral immunity remains elusive. Here, we report that the O-GlcNAcylation of mitochondrial antiviral-signaling protein (MAVS), a key mediator of interferon...

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Bibliographic Details
Main Authors: Nan Song, Qi Qi, Ruiyuan Cao, Bingjie Qin, Bo Wang, Yuxia Wang, Lei Zhao, Wei Li, Xianli Du, Feng Liu, Yunzheng Yan, Wen Yi, Hailu Jiang, Tao Li, Tao Zhou, Hui-yan Li, Qing Xia, Xue-min Zhang, Wu Zhong, Ai-ling Li, Xiaotao Duan
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719310010

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http://www.sciencedirect.com/science/article/pii/S2211124719310010

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