Hypoxia promotes dopaminergic differentiation of mesenchymal stem cells and shows benefits for transplantation in a rat model of Parkinson's disease.

Hypoxia promotes dopaminergic differentiation of mesenchymal stem cells and shows benefits for transplantation in a rat model of Parkinson's disease.

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into dopaminergic (DAergic) neurons, which is one of the major cell types damaged in Parkinson's disease (PD). For this reason, MSCs are considered a potential cell source for PD therapy. It has been proved that hypo...

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Bibliographic Details
Main Authors:	Yue Wang, Jian Yang, Haisheng Li, Xuan Wang, Lingling Zhu, Ming Fan, Xiaomin Wang
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3546985?pdf=render

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