Study on the Mechanism of miR-34a Affecting the Proliferation, Migration, and Invasion of Human Keloid Fibroblasts by Regulating the Expression of SATB1

Objectives. To explore the effect and mechanism of miR-34a on the proliferation, migration, and invasion of keloid fibroblasts (KFB). Methods. Isolate and culture KFB and normal skin fibroblast (NFB), detect the mRNA expression levels of miR-34a and integrin β5 (SATB1) in KFB and NFB by RT-qPCR, and...

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Bibliographic Details
Main Authors: Lei Jiang, Xiufang Shi, Meng Wang, Huaxia Chen
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Healthcare Engineering
Online Access:http://dx.doi.org/10.1155/2021/8741512