Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle

The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.

Bibliographic Details
Main Authors:	Moon Kyoo Jang, Alison A. McBride
Format:	Article
Language:	English
Published:	MDPI AG 2013-05-01
Series:	Viruses
Subjects:	Brd4 BET protein HPV papillomavirus transcription chromatin replication tethering partitioning bromodomain
Online Access:	http://www.mdpi.com/1999-4915/5/6/1374

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spelling	doaj-a76c68c8ae9a424abebc4a574dc2a0642020-11-24T21:48:37ZengMDPI AGViruses1999-49152013-05-01561374139410.3390/v5061374Current Understanding of the Role of the Brd4 Protein in the Papillomavirus LifecycleMoon Kyoo JangAlison A. McBrideThe Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.http://www.mdpi.com/1999-4915/5/6/1374Brd4BET proteinHPVpapillomavirustranscriptionchromatinreplicationtetheringpartitioningbromodomain
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Moon Kyoo Jang Alison A. McBride
spellingShingle	Moon Kyoo Jang Alison A. McBride Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle Viruses Brd4 BET protein HPV papillomavirus transcription chromatin replication tethering partitioning bromodomain
author_facet	Moon Kyoo Jang Alison A. McBride
author_sort	Moon Kyoo Jang
title	Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
title_short	Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
title_full	Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
title_fullStr	Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
title_full_unstemmed	Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle
title_sort	current understanding of the role of the brd4 protein in the papillomavirus lifecycle
publisher	MDPI AG
series	Viruses
issn	1999-4915
publishDate	2013-05-01
description	The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.
topic	Brd4 BET protein HPV papillomavirus transcription chromatin replication tethering partitioning bromodomain
url	http://www.mdpi.com/1999-4915/5/6/1374
work_keys_str_mv	AT moonkyoojang currentunderstandingoftheroleofthebrd4proteininthepapillomaviruslifecycle AT alisonamcbride currentunderstandingoftheroleofthebrd4proteininthepapillomaviruslifecycle
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Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle

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