The effects of combination treatments on drug resistance in chronic myeloid leukaemia: an evaluation of the tyrosine kinase inhibitors axitinib and asciminib
Abstract Background Chronic myeloid leukaemia is in principle a treatable malignancy but drug resistance is lowering survival. Recent drug discoveries have opened up new options for drug combinations, which is a concept used in other areas for preventing drug resistance. Two of these are (I) Axitini...
Main Authors: | H. Jonathan G. Lindström, Ran Friedman |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
|
Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-020-06782-9 |
Similar Items
-
Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia
by: H. Jonathan G. Lindström, et al.
Published: (2019-05-01) -
Asciminib Mitigates DNA Damage Stress Signaling Induced by Cyclophosphamide in the Ovary
by: Luca Mattiello, et al.
Published: (2021-01-01) -
Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies
by: Zhendong Song, et al.
Published: (2021-01-01) -
Combating drug resistance in acute myeloid leukaemia by drug rotations: the effects of quizartinib and pexidartinib
by: Jingmei Yang, et al.
Published: (2021-04-01) -
Data set of competitive and allosteric protein kinase inhibitors confirmed by X-ray crystallography
by: Huabin Hu, et al.
Published: (2021-04-01)