Interactions between procedural learning and cocaine exposure alter spontaneous and cortically-evoked spike activity in the dorsal striatum

Interactions between procedural learning and cocaine exposure alter spontaneous and cortically-evoked spike activity in the dorsal striatum

We have previously shown that cocaine enhances gene regulation in the sensorimotor striatum associated with procedural learning in a running-wheel paradigm. Here we assessed whether cocaine produces enduring modifications of learning-related changes in striatal neuron activity, using single-unit rec...

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Bibliographic Details
Main Authors: Janie eOndracek, Ingo eWilluhn, Heinz eSteiner, Anthony R West
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-12-01
Series:Frontiers in Neuroscience
Subjects:
Addiction
Habit formation
Corticostriatal transmission
dorsal striatum
medium-sized spiny neuron
procedural learning
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2010.00206/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2010.00206/full

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