Signatures of host-pathogen evolutionary conflict reveal MISTR-A conserved MItochondrial STress Response network.
Host-pathogen conflicts leave genetic signatures in genes that are critical for host defense functions. Using these "molecular scars" as a guide to discover gene functions, we discovered a vertebrate-specific MItochondrial STress Response (MISTR) circuit. MISTR proteins are associated with...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-12-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3001045 |