Curcumin-loaded chitosan–bovine serum albumin nanoparticles potentially enhanced Aβ 42 phagocytosis and modulated macrophage polarization in Alzheimer’s disease

Curcumin-loaded chitosan–bovine serum albumin nanoparticles potentially enhanced Aβ 42 phagocytosis and modulated macrophage polarization in Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder in the elderly population. In the treatment of AD, some obstacles, including drug penetration difficulty through the blood–brain barrier (BBB), inadequate clearance of the Aβ peptide, and the massive release of inflammat...

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Bibliographic Details
Main Authors: Rui Yang, Yan Zheng, Qingjun Wang, Liang Zhao
Format: Article
Language:English
Published: SpringerOpen 2018-10-01
Series:Nanoscale Research Letters
Subjects:
Alzheimer’s disease
Blood–brain barrier
Aβ peptide
Nanoparticles
Curcumin
Online Access:http://link.springer.com/article/10.1186/s11671-018-2759-z

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http://link.springer.com/article/10.1186/s11671-018-2759-z

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