Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy

Different physiological and pathological conditions can perturb protein folding in the endoplasmic reticulum, leading to a condition known as ER stress. ER stress activates a complex intracellular signal transduction pathway, called unfolded protein response (UPR). The UPR is tailored essentially to...

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Bibliographic Details
Main Authors: Tom Verfaillie, Maria Salazar, Guillermo Velasco, Patrizia Agostinis
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2010/930509