Fermentative Production of the Diamine Putrescine: System Metabolic Engineering of Corynebacterium Glutamicum

Fermentative Production of the Diamine Putrescine: System Metabolic Engineering of Corynebacterium Glutamicum

Corynebacterium glutamicum shows great potential for the production of the glutamate-derived diamine putrescine, a monomeric compound of polyamides. A genome-scale stoichiometric model of a C. glutamicum strain with reduced ornithine transcarbamoylase activity, derepressed arginine biosynthesis, and...

Full description

Bibliographic Details
Main Authors: Anh Q. D. Nguyen, Jens Schneider, Gajendar Komati Reddy, Volker F. Wendisch
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Metabolites
Subjects:
diamine production
putrescine
Corynebacterium glutamicum
2-oxoglutatarate dehydrogenase
pyruvate carboxylase
glyceraldehyde 3-phosphate dehydrogenase
OdhI
spermidine N-acetyltransferase
CgmR
N-acetylglutamate kinase
gamma-glutamate kinase
genome-scale metabolic model
flux balance analysis
Online Access:http://www.mdpi.com/2218-1989/5/2/211

Internet

http://www.mdpi.com/2218-1989/5/2/211

Similar Items