Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

<p>Abstract</p> <p>Background</p> <p>Microglial activation is an important histologic characteristic of the pathology of Alzheimer’s disease (AD). One hypothesis is that amyloid beta (Aβ) peptide serves as a specific stimulus for tyrosine kinase-based microglial activat...

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Bibliographic Details
Main Authors: Dhawan Gunjan, Combs Colin K
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/117