A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum

A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum

2,3,5,4,-Tetrahydroxystilbene-2-O-β-d-glucoside (TSG) is the main active constituent of the traditional Chinese medicine, Polygonum multiflorum; it was discovered that the compound has various biological activities and medicinal value including anti-aging, antioxidative (via scavenging free radicals...

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Main Authors: Jin Qian, Mingqi Hou, Xian Wu, Chuanying Dai, Jiaqiang Sun, Liuyi Dong
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Tetrahydroxystilbene
Polygonummultiflorum
Pharmacological activities
Traditional Chinese medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222030113X
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spelling doaj-a732eea54c734b5392ee1697c06532052021-05-20T07:40:40ZengElsevierBiomedicine & Pharmacotherapy0753-33222020-04-01124109923A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorumJin Qian0Mingqi Hou1Xian Wu2Chuanying Dai3Jiaqiang Sun4Liuyi Dong5Department of Pharmacology, Key Laboratory of Anti-Inflammatory and Immunopharmacology of Ministry of Education, Key Laboratory of Chinese Medicine Research and Development of State Administration of Traditional Chinese Medicine, Anhui Medical University, Hefei, 230032, ChinaDepartment of Pharmacology, Key Laboratory of Anti-Inflammatory and Immunopharmacology of Ministry of Education, Key Laboratory of Chinese Medicine Research and Development of State Administration of Traditional Chinese Medicine, Anhui Medical University, Hefei, 230032, ChinaDepartment of Pharmacology, Key Laboratory of Anti-Inflammatory and Immunopharmacology of Ministry of Education, Key Laboratory of Chinese Medicine Research and Development of State Administration of Traditional Chinese Medicine, Anhui Medical University, Hefei, 230032, ChinaDepartment of Pharmacology, Key Laboratory of Anti-Inflammatory and Immunopharmacology of Ministry of Education, Key Laboratory of Chinese Medicine Research and Development of State Administration of Traditional Chinese Medicine, Anhui Medical University, Hefei, 230032, ChinaDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, Hefei, 230001 China; Corresponding author at: Department of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of USTC, 17 Lujiang Road, Hefei, Anhui, 230001, China.Department of Pharmacology, Key Laboratory of Anti-Inflammatory and Immunopharmacology of Ministry of Education, Key Laboratory of Chinese Medicine Research and Development of State Administration of Traditional Chinese Medicine, Anhui Medical University, Hefei, 230032, China; Corresponding author at: Department of Pharmacology, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, 230032, China.2,3,5,4,-Tetrahydroxystilbene-2-O-β-d-glucoside (TSG) is the main active constituent of the traditional Chinese medicine, Polygonum multiflorum; it was discovered that the compound has various biological activities and medicinal value including anti-aging, antioxidative (via scavenging free radicals), antihypercholesterolemic, anti-atherosclerotic, anti-inflammatory, hepatoprotective, and anti-tumor effects. TSG aids in prevention and treatment of Alzheimer's disease. With its wide clinical application, its separation and purification has become a research hotspot. In this paper, the pharmacological action, extraction process, and application prospects of TSG were reviewed in order to provide references for further development of TSG.http://www.sciencedirect.com/science/article/pii/S075333222030113XTetrahydroxystilbenePolygonummultiflorumPharmacological activitiesTraditional Chinese medicine
collection DOAJ
language English
format Article
sources DOAJ
author Jin Qian
Mingqi Hou
Xian Wu
Chuanying Dai
Jiaqiang Sun
Liuyi Dong
spellingShingle Jin Qian
Mingqi Hou
Xian Wu
Chuanying Dai
Jiaqiang Sun
Liuyi Dong
A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
Biomedicine & Pharmacotherapy
Tetrahydroxystilbene
Polygonummultiflorum
Pharmacological activities
Traditional Chinese medicine
author_facet Jin Qian
Mingqi Hou
Xian Wu
Chuanying Dai
Jiaqiang Sun
Liuyi Dong
author_sort Jin Qian
title A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
title_short A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
title_full A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
title_fullStr A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
title_full_unstemmed A review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-d-glucoside from Polygonum multiflorum
title_sort review on the extraction, purification, detection, and pharmacological effects of 2,3,5,4’-tetrahydroxystilbene-2-o-β-d-glucoside from polygonum multiflorum
publisher Elsevier
series Biomedicine & Pharmacotherapy
issn 0753-3322
publishDate 2020-04-01
description 2,3,5,4,-Tetrahydroxystilbene-2-O-β-d-glucoside (TSG) is the main active constituent of the traditional Chinese medicine, Polygonum multiflorum; it was discovered that the compound has various biological activities and medicinal value including anti-aging, antioxidative (via scavenging free radicals), antihypercholesterolemic, anti-atherosclerotic, anti-inflammatory, hepatoprotective, and anti-tumor effects. TSG aids in prevention and treatment of Alzheimer's disease. With its wide clinical application, its separation and purification has become a research hotspot. In this paper, the pharmacological action, extraction process, and application prospects of TSG were reviewed in order to provide references for further development of TSG.
topic Tetrahydroxystilbene
Polygonummultiflorum
Pharmacological activities
Traditional Chinese medicine
url http://www.sciencedirect.com/science/article/pii/S075333222030113X
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