The role of cholesterol metabolism and cholesterol transport in carcinogenesis; A review of scientific findings, relevant to future cancer therapeutics.

While the unique metabolic activities of malignant tissues as potential targets for cancer therapeutics has been the subject of several recent reviews, the role of cholesterol metabolism in this context is yet to be fully explored. Cholesterol is an essential component of mammalian cell membranes as...

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Bibliographic Details
Main Authors: Pedro Miguel Cruz, Huanbiao eMo, Walter eMcConathy, Nirupama Avinash Sabnis, Andras G Lacko
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Pharmacology
Subjects:
L
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00119/full