Ten-eleven translocation-2 affects the fate of cells and has therapeutic potential in digestive tumors

Ten-eleven translocation (TET) methylcytosine dioxygenases catalyze the oxidative reactions of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC), and 5-carboxylcytosine (5-caC), which are intermediate steps during DNA demethylation. It is reported that somatic mutat...

Full description

Bibliographic Details
Main Authors: Feng Wang, Jing Zhang, Jian Qi
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-12-01
Series:Chronic Diseases and Translational Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2095882X19300878

Similar Items