Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells

Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells

Cardiomyocytes hypertrophy and apoptosis induced by advanced glycation end products (AGEs) is the crucial pathological foundation contributing to the onset and development of diabetic cardiomyopathy (DCM). However, the mechanism remains poorly understood. Here, we report that profilin-1 (PFN-1), a w...

Full description

Bibliographic Details
Main Authors: Dafeng Yang, Ya Wang, Minna Jiang, Xu Deng, Zhifang Pei, Fei Li, Ke Xia, Lingyan Zhu, Tianlun Yang, Meifang Chen
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/9716087

Internet

http://dx.doi.org/10.1155/2017/9716087

Similar Items