Zika Virus Fatally Infects Wild Type Neonatal Mice and Replicates in Central Nervous System

Zika Virus Fatally Infects Wild Type Neonatal Mice and Replicates in Central Nervous System

Zika virus (ZIKV) has been defined as a teratogenic pathogen behind the increased number of cases of microcephaly in French Polynesia, Brazil, Puerto Rico, and other South American countries. Experimental studies using animal models have achieved tremendous insight into understanding the viral patho...

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Bibliographic Details
Main Authors: Shuxuan Li, Najealicka Armstrong, Huan Zhao, Wangheng Hou, Jian Liu, Chunye Chen, Junkai Wan, Wei Wang, Chunlian Zhong, Che Liu, Hua Zhu, Ningshao Xia, Tong Cheng, Qiyi Tang
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Viruses
Subjects:
Zika virus (ZIKV)
neonatal mouse
pathogenesis
microcephaly
Flavivirus
Online Access:http://www.mdpi.com/1999-4915/10/1/49

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