Disturbance of Response to Acute Thermal Pain in Naturally Occurring Cholecystokinin-A Receptor Gene Knockout Otsuka Long-Evans Tokushima Fatty (OLETF) Rats

Abstract.: Otsuka Long-Evans Tokushima Fatty (OLETF) rats lack cholecystokinin-A receptor (CCK-AR) because of a genetic abnormality. We observed that body temperature homeostasis in response to changes in ambient temperature was deteriorated in OLETF rats, while the functions of the signal outputs f...

Full description

Bibliographic Details
Main Authors: Miyasaka Kyoko, Nomoto Shigeki, Ohta Minoru, Kanai Setsuko, Kaneko Takao, Tahara Shoichi, Funakoshi Akihiro
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344317