Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats

Psychological stress may alter gastrointestinal absorptive function by increasing the quantity of intestinal free radicals or by lowering endogenous intestinal free radical scavenging capacity. Vitamin E has been shown to be a potent endogenous antioxidant and free radical scavenger under both physi...

Full description

Bibliographic Details
Main Authors: Scott Burdick, Ningren Cui, Lonnie R Empey, Richard N Fedorak
Format: Article
Language:English
Published: Hindawi Limited 1994-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1994/712352
id doaj-a6f2998fcf46486e9f2965073cfbaf27
record_format Article
spelling doaj-a6f2998fcf46486e9f2965073cfbaf272020-11-24T22:44:07ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79001994-01-018741742110.1155/1994/712352Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in RatsScott Burdick0Ningren Cui1Lonnie R Empey2Richard N Fedorak3Division of Gasrroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gasrroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gasrroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gasrroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaPsychological stress may alter gastrointestinal absorptive function by increasing the quantity of intestinal free radicals or by lowering endogenous intestinal free radical scavenging capacity. Vitamin E has been shown to be a potent endogenous antioxidant and free radical scavenger under both physiological and pathological conditions. The purpose of this study was to determine whether cold wrap restraint stress altered in vivo intestinal fluid absorption in rats, and whether vitamin E administration prior to the induction of cold wrap restraint stress could prevent such changes in intestinal secretion. Jejunal, ileal and colonic fluid and electrolyte transport rates were measured in vivo using an isolated loop technique. Cold wrap restraint stress reduced in vivo fluid absorption in the ileum and colon, but not in the jejunum. Administration of vitamin E prior to the cold wrap restraint stress procedure completely prevented this alteration of ileal and colonic fluid absorption.http://dx.doi.org/10.1155/1994/712352
collection DOAJ
language English
format Article
sources DOAJ
author Scott Burdick
Ningren Cui
Lonnie R Empey
Richard N Fedorak
spellingShingle Scott Burdick
Ningren Cui
Lonnie R Empey
Richard N Fedorak
Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
Canadian Journal of Gastroenterology
author_facet Scott Burdick
Ningren Cui
Lonnie R Empey
Richard N Fedorak
author_sort Scott Burdick
title Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
title_short Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
title_full Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
title_fullStr Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
title_full_unstemmed Vitamin E Prevents Cold Wrap Restraint Stress-Induced Intestinal Fluid Transport Alterations in Rats
title_sort vitamin e prevents cold wrap restraint stress-induced intestinal fluid transport alterations in rats
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 1994-01-01
description Psychological stress may alter gastrointestinal absorptive function by increasing the quantity of intestinal free radicals or by lowering endogenous intestinal free radical scavenging capacity. Vitamin E has been shown to be a potent endogenous antioxidant and free radical scavenger under both physiological and pathological conditions. The purpose of this study was to determine whether cold wrap restraint stress altered in vivo intestinal fluid absorption in rats, and whether vitamin E administration prior to the induction of cold wrap restraint stress could prevent such changes in intestinal secretion. Jejunal, ileal and colonic fluid and electrolyte transport rates were measured in vivo using an isolated loop technique. Cold wrap restraint stress reduced in vivo fluid absorption in the ileum and colon, but not in the jejunum. Administration of vitamin E prior to the cold wrap restraint stress procedure completely prevented this alteration of ileal and colonic fluid absorption.
url http://dx.doi.org/10.1155/1994/712352
work_keys_str_mv AT scottburdick vitaminepreventscoldwraprestraintstressinducedintestinalfluidtransportalterationsinrats
AT ningrencui vitaminepreventscoldwraprestraintstressinducedintestinalfluidtransportalterationsinrats
AT lonnierempey vitaminepreventscoldwraprestraintstressinducedintestinalfluidtransportalterationsinrats
AT richardnfedorak vitaminepreventscoldwraprestraintstressinducedintestinalfluidtransportalterationsinrats
_version_ 1725692905074458624