Whole Genome Characterization and Genetic Evolution Analysis of a New Ostrich Parvovirus

• Main Authors: Kunpeng Yuan, Dongdong Wang, Qingdong Luan, Ju Sun, Qianwen Gao, Zhiyao Jiang, Shouchun Wang, Yijun Han, Xueting Qu, Yueying Cui, Shimei Qiu, Youxia Di, Xiaoyi Wang, Shige Song, Peiheng Wang, Shilong Xia, Yongle Yu, Weiquan Liu, Yanbo Yin
• Format: Article
• Language: English
• Published: MDPI AG 2020-03-01
• Series: Viruses
• Subjects: ostrich; leg paralysis; parvovirus; phylogenetic analysis; whole genome amplification
• Online Access: https://www.mdpi.com/1999-4915/12/3/334

Ostrich diseases characterized by paralysis have been breaking out in broad areas of China since 2015, causing major damage to the ostrich breeding industry in China. This report describes a parvovirus detected in ostriches from four different regions. The entire genomes of four parvovirus strains were sequenced following amplification by PCR, and we conducted comprehensive analysis of the ostrich parvovirus genome. Results showed that the length genomes of the parvovirus contained two open reading frames. Ostrich parvovirus (OsPV) is a branch of goose parvovirus (GPV). Genetic distance analysis revealed a close relationship between the parvovirus and goose parvovirus strains from China, with the closest being the 2016 goose parvovirus RC16 strain from Chongqing. This is the first report of a parvovirus in ostriches. However, whether OsPV is the pathogen of ostrich paralysis remains uncertain. This study contributes new information about the evolution and epidemiology of parvovirus in China, which provides a new way for the study of paralysis in ostriches.