Recommendations for the usage and treatment with fresh frozen plasma
Fresh frozen plasma (FFP) is a blood component obtained from processed whole blood or collected by plasmapheresis and afterwards stored in frozen state. Indications for the clinical use of FFP are single coagulation factor deficiencies (such as F V and F XI), multiple coagulation factors defic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2012-01-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/552 |
| Summary: | Fresh frozen plasma (FFP) is a blood component
obtained from processed whole blood or collected
by plasmapheresis and afterwards stored in
frozen state. Indications for the clinical use of
FFP are single coagulation factor deficiencies
(such as F V and F XI), multiple coagulation factors
deficiency (most frequent as a consequence
of massive hemorrhage), coagulopathy caused
by advanced liver disease, warfarin mediated
coagulopathy and thrombotic thrombocytopenic
purpura. Standard FFP treatment dose in
mentioned indications is generally 10–20 ml/kg
of patient body weight. During the treatment attention
should be paid to possible FFP treatment
related adverse effects. Most frequent are allergic
reactions. We should not consider FFP as a treatment approach in clinical situations where equally effective and safer treatment modalities are available. |
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| ISSN: | 1318-0347 1581-0224 |