Lrp4 domains differentially regulate limb/brain development and synaptic plasticity.

Apolipoprotein E (ApoE) genotype is the strongest predictor of Alzheimer's Disease (AD) risk. ApoE is a cholesterol transport protein that binds to members of the Low-Density Lipoprotein (LDL) Receptor family, which includes LDL Receptor Related Protein 4 (Lrp4). Lrp4, together with one of its...

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Bibliographic Details
Main Authors: Theresa Pohlkamp, Murat Durakoglugil, Courtney Lane-Donovan, Xunde Xian, Eric B Johnson, Robert E Hammer, Joachim Herz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331535?pdf=render