Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer

Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer

Brain metastasis frequently develops in non-small-cell lung cancer (NSCLC). Here, we report a patient who developed brain metastasis from ALK-positive NSCLC which mimicked brain abscess. He was admitted for suspected obstructive pneumonia nine months after curative lung resection. Head magnetic reso...

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Main Authors: Toshio Sakatani, Hidenori Kage, Shunsaku Takayanagi, Kaoru Watanabe, Yoshihisa Hiraishi, Aya Shinozaki-Ushiku, Shota Tanaka, Tetsuo Ushiku, Nobuhito Saito, Takahide Nagase
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2019/9141870
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spelling doaj-a6e0f4a5ac274432af7dc3d6a3d56e5a2020-11-24T21:32:49ZengHindawi LimitedCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/91418709141870Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung CancerToshio Sakatani0Hidenori Kage1Shunsaku Takayanagi2Kaoru Watanabe3Yoshihisa Hiraishi4Aya Shinozaki-Ushiku5Shota Tanaka6Tetsuo Ushiku7Nobuhito Saito8Takahide Nagase9Department of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Neurosurgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Neurosurgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Pathology, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Neurosurgery, Graduate School of Medicine, University of Tokyo, Tokyo, JapanDepartment of Respiratory Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, JapanBrain metastasis frequently develops in non-small-cell lung cancer (NSCLC). Here, we report a patient who developed brain metastasis from ALK-positive NSCLC which mimicked brain abscess. He was admitted for suspected obstructive pneumonia nine months after curative lung resection. Head magnetic resonance imaging revealed a cavitary lesion, which was compatible with brain abscess but rare in brain metastasis. However, after treatment with antibiotics, the brain lesion increased in size. Aspiration of the liquid content of the brain lesion revealed cancer cells. When a brain lesion suggestive of abscess develops in a patient with ALK-positive NSCLC, aspiration may be necessary to differentiate metastasis from abscess.http://dx.doi.org/10.1155/2019/9141870
collection DOAJ
language English
format Article
sources DOAJ
author Toshio Sakatani
Hidenori Kage
Shunsaku Takayanagi
Kaoru Watanabe
Yoshihisa Hiraishi
Aya Shinozaki-Ushiku
Shota Tanaka
Tetsuo Ushiku
Nobuhito Saito
Takahide Nagase
spellingShingle Toshio Sakatani
Hidenori Kage
Shunsaku Takayanagi
Kaoru Watanabe
Yoshihisa Hiraishi
Aya Shinozaki-Ushiku
Shota Tanaka
Tetsuo Ushiku
Nobuhito Saito
Takahide Nagase
Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
Case Reports in Oncological Medicine
author_facet Toshio Sakatani
Hidenori Kage
Shunsaku Takayanagi
Kaoru Watanabe
Yoshihisa Hiraishi
Aya Shinozaki-Ushiku
Shota Tanaka
Tetsuo Ushiku
Nobuhito Saito
Takahide Nagase
author_sort Toshio Sakatani
title Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
title_short Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
title_full Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
title_fullStr Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
title_full_unstemmed Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer
title_sort brain metastasis mimicking brain abscess in alk-positive non-small-cell lung cancer
publisher Hindawi Limited
series Case Reports in Oncological Medicine
issn 2090-6706
2090-6714
publishDate 2019-01-01
description Brain metastasis frequently develops in non-small-cell lung cancer (NSCLC). Here, we report a patient who developed brain metastasis from ALK-positive NSCLC which mimicked brain abscess. He was admitted for suspected obstructive pneumonia nine months after curative lung resection. Head magnetic resonance imaging revealed a cavitary lesion, which was compatible with brain abscess but rare in brain metastasis. However, after treatment with antibiotics, the brain lesion increased in size. Aspiration of the liquid content of the brain lesion revealed cancer cells. When a brain lesion suggestive of abscess develops in a patient with ALK-positive NSCLC, aspiration may be necessary to differentiate metastasis from abscess.
url http://dx.doi.org/10.1155/2019/9141870
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