Molecular diagnosis of prostate cancer: Topical issues

Molecular diagnosis of prostate cancer: Topical issues

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Prostate cancer (PC) is the second most common cancer and the fifth highest malignancy mortality rate in men worldwide. Although PC is detectable in 15-20% of men during life, its death risk is only about 3%. This means that not all PC cases require the same management tactics. The given review anal...

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Bibliographic Details
Main Authors: E. N. Knyazev, K. A. Fomicheva, K. M. Nyushko, A. D. Kaprin, B. Ya. Alekseev, M. Yu. Shkurnikov
Format: Article
Language:Russian
Published: ABV-press 2014-12-01
Series:Onkourologiâ
Subjects:
prostate cancer
molecular genetic markers
receptors
membrane proteins
heat shock protein
transcriptome
gene fusion
matrix ribonucleic acids
prostate cancer antigen 3
polymerase chain reaction
expression
hyperactivation
Online Access:https://oncourology.abvpress.ru/oncur/article/view/391
Description
Summary:Prostate cancer (PC) is the second most common cancer and the fifth highest malignancy mortality rate in men worldwide. Although PC is detectable in 15-20% of men during life, its death risk is only about 3%. This means that not all PC cases require the same management tactics. The given review analyzes the current investigations searching for molecular biological markers to predict the course of PC and to choose its treatment policy, including that in the development of resistance to androgen-deprivation therapy.
ISSN:1726-9776
1996-1812

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