Identification of Gender-Specific Molecular Differences in Glioblastoma (GBM) and Low-Grade Glioma (LGG) by the Analysis of Large Transcriptomic and Epigenomic Datasets

Identification of Gender-Specific Molecular Differences in Glioblastoma (GBM) and Low-Grade Glioma (LGG) by the Analysis of Large Transcriptomic and Epigenomic Datasets

Differences in the incidence and outcome of glioma between males and females are well known, being more striking for glioblastoma (GB) than low-grade glioma (LGG). The extensive and well-annotated data in publicly available databases enable us to analyze the molecular basis of these differences at a...

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Bibliographic Details
Main Authors: Md Tipu Khan, Bharat Prajapati, Simran Lakhina, Mridula Sharma, Sachin Prajapati, Kunzang Chosdol, Subrata Sinha
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
glioblastoma multiforme
low-grade glioma (LGG)
transcriptomics
epigenetics
weighted gene co-expression network analysis (WGCNA)
pathway analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.699594/full

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