Assessment of One-, Three- and Five-Year Survival Rates in Patients with Colon Cancer in Hamedan Province from 2003 to 2017

• Main Authors: Rasoul Najafi, Fatemeh Amiri, Ghodratoalleh Roshanaei, Mohammad Abbasi
• Format: Article
• Language: fas
• Published: Arak Medical University 2019-06-01
• Series: Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk
• Subjects: Colon cancer; Cox regression; Kaplan mayer
• Online Access: http://jams.arakmu.ac.ir/article-1-5960-en.html
• ISSN: 1735-5338; 2008-644X

Background and Aim: Colon cancer is one of the most common cancers in the gastrointestinal tract. Colon cancer is the third death cause among cancers. The aim of this study was to estimate the survival rate and determine the effective factors in colon cancer patients. Materials and Methods: In this study, 193 colon cancer patients referring to Hamadan Imam Khomeini Clinic during the years 2003-2017 in a retrospective cohort study were used. Follow up of all patients was done by referral and phone call up to 2017. The Kaplan -Meyer model was used to estimate the survival of patients. Also, the effect of prognostic factors on the survival of patients was obtained by Cox regression model. The software used to analyze the data was STATA 11 and the significance level was 0.05. Ethical Considerations: This study with research ethics code IR.UMSHA.REC.1396.144 was approved in Research Ethics Committee of Hamadan University of medical sciences, Iran. Findings: The mean age of the patients at diagnosis was 57.09 ± 12.9 years. The probability of survival of one-, three- and five-year was 0.82, 0.61 and 0.48 percent, respectively. Also, the cancer stage has a significant effect on survival time of the patients. Conclusion: Based on the Cox model, only the stage of cancer was effective on the survival time of patients with colon cancer. Therefore, timely diagnosis also helps prevent disease progression, as well as increase the survival time of the patient, especially at an advanced age.