A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein.

The coronavirus E protein is a small membrane protein with a single predicted hydrophobic domain (HD), and has a poorly defined role in infection. The E protein is thought to promote virion assembly, which occurs in the Golgi region of infected cells. It has also been implicated in the release of in...

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Bibliographic Details
Main Authors: Travis R Ruch, Carolyn E Machamer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3343006?pdf=render