PLK1, A Potential Target for Cancer Therapy

Polo-like kinase 1 (PLK1) plays an important role in the initiation, maintenance, and completion of mitosis. Dysfunction of PLK1 may promote cancerous transformation and drive its progression. PLK1 overexpression has been found in a variety of human cancers and was associated with poor prognoses in...

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Bibliographic Details
Main Authors: Zhixian Liu, Qingrong Sun, Xiaosheng Wang
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523316301371