Role of estrogen receptors (ERs) and G protein-coupled estrogen receptor (GPER) in regulation of hypothalamic-pituitary-testis axis and spermatogenesis

Role of estrogen receptors (ERs) and G protein-coupled estrogen receptor (GPER) in regulation of hypothalamic-pituitary-testis axis and spermatogenesis

Male reproductive function is under the control of both gonadotropins and androgens through a negative feedback loop that involves the hypothalamus, pituitary and testis known as hypothalamus-pituitary-gonadal axis (HPG). Indeed, also estrogens play an important role in regulating HPG axis but the r...

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Bibliographic Details
Main Authors: Adele eChimento, Rosa eSirianni, Ivan eCasaburi, Vincenzo ePezzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Endocrinology
Subjects:
Gonadotropins
Spermatogenesis
HPG axis
GPER
ESR1
ESR2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00001/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00001/full

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